MACROGOL products are polyethylene glycols which conform to the Japanese
Pharmacopoeia (JP) and also the Japanese Pharmaceutical Excipients (JPE).
They are expressed in the following general formula:
HOCH2(CH2OCH2)nCH2OH
The appearance of MACROGOL products varies depending on the molecular weight.
For example, MACROGOL 400 is a viscous liquid, while MACROGOL 1500 is a
paste-like solid substance and MACROGOL 6000 is a waxy solid substance,
the later is available in either flakes or powder. Each MACROGOL product
is water-soluble, and has low toxicity (LD50 values). These features make MACROGOL ideal for use as a base material for ointments and suppositories, tablet coating agents, tablet binders, and other applications.
