POLYQUID PA-30
Outline
Coating Agents for Oral Solid Preparations, Binders and Excipients, Methacrylic Acid Copolymer LD
Features
· An enteric-soluble coating agent (methacrylic acid copolymer dispersion).
· Used effectively for granules, oral capsules and tablets as coating agents for oral solid preparations, binders and excipients.
· Drug release at any site of digestion. Small intestine (upper part) pH:5 to 7 and Small intestine (lower part) and large intestine pH:6 to 8.
· Having excellent low-film forming temperature property.
· Coating agents - The coating film made by this product on tablets and granules can mask the taste, protect active ingredients, release the drug at any site of digestion and allow sustained release of the drug.
· Protection of active ingredients, and taste masking.
· Binders and excipients - Used for binders for wet granulation method based water or organic solvent.
· It conforms to JPE, USP/NF and EP.
· Enteric coating (US DMF 16349).
Functions
- ・Adhesive
- ・Reacting/Forming
- ・Others
Applications
- ・Pharmaceuticals/Quasi-Drugs/Medical Supplies
Composition
Methacrylate/Acrylate-based Polymethacrylate-type
Properties, and other information
| Appearance | Opaque white liquid | pH(Sample Concentration) | 2.5 | Viscosity（mPa･s） | 9 |
| Methacrylic acid / ethyl acrylate-containing mole ratio | 1/0.85 | Specific Gravity | （20/20）1.068 ＜20/04＞1.065 |
Precaution Against Mishandling
· It may precipitate copolymer components if it is strongly agitated. Set the optimum stirring conditions according to the coating liquid preparation equipment.
· The efficacy and stability of the drug product vary depending on the drug used in combination, its amount, manufacturing method, and usage. Test it in advance and use it within the range where there is no problem.
· Determine the optimal agitation conditions for POLYQUID PA-30 according to the apparatus applied because copolymer ingredients may be separated out when it is rapidly agitated.
· Use this product after ensuring the performance to allow it to exert its expected performance, because the effects, and stability depend on the conditions such as other agents added, the amounts, formula, directions for use, etc.
Other Precautions
Store indoors at 5 − 25 °C and keep containers tightly closed to protect this product from deterioration.
Before handling this product, refer to the current Safety Data Sheet for recommended protective equipment, and detailed precautionary and hazards information.If SDS is not listed on the homepage, please contact our sales representative.
